The application is straightforward. For instance, Sri Mahatma Gandhi was born in Tula Lagna, and his 9th house is in Mithuna. Now what are the results of Mithuna?
Mithuna is a Saumya Rasi (gentle sign) and is owned by Budha, the scholar. These are reflected in the effects of the 9th house the native.
The person with Mithuna in the 9th house likes hosting and looking after guests, feeding Brahmins, charity for the poor and downtrodden, is a keeper of dharma through many kinds of righteous, charitable and philanthropic activities.
Many of these effects are true for Gandhiji. He was deeply religious and believed in chanting the names of Rama and studying Ramayana. He worked for the upliftment of the masses.
But this is not all, because, the results are modified by the Grahas in the 9th house, and the disposition of the 9th lord. Budha is in the Lagna in a Saumya Rasi, with Shukra. He considered that it was his ordained destiny to work for the freedom movement through non violent means (Budha = Non violence, that is supported by Shukra). Be he fought for the country's freedom because, the Grahas are conjunct Mangala in the Lagna.